Postnatal outcomes from prenatal ultrasound in LUTO

Article DOIhttps://doi.org/10.1002/uog.29129
ObjectiveTo predict postnatal outcome in fetuses with lower urinary tract obstruction (LUTO) using prenatal ultrasound findings
AI ApproachRandom forrest
Data Source(s)Single institutional series (125 patients)
Model InputGestational age (GA) at initial visit, indication for referral, fetal sex, suspected prenatal diagnosis and confirmed postnatal diagnosis, ultrasound features, genetic anomalies, maternal demographics and prenatal interventions
Model OutcomeNeed for transplant
Need for dialysis
Death
Model MetricsPredict transplant: AUC 0.65, 77% accuracy, 50% sensitivity, 80% specificity
 
Predict death: AUC 0.78, 72% accuracy, 83% sensitivity, 67% specificity
 
Predict dialysis: AUC 0.69, 71% accuracy, 70% sensitivity, 71% specificity
Model UsabilityGitHub repository (https://github.com/larunerdman/PrenatalLUTO) with example data and script used for this project.

AI = Artificial intelligence, LUTO = Lower urinary tract obstruction, AUC = Area under the receiver operator characteristic

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