To categorize bladder dysfunction in Spina Bifida, LUTD

Article DOIhttps://doi.org/10.1097/JU.0000000000003267
ObjectiveTo develop deep
learning models of VUDS to categorize severity of bladder dysfunction in patients with spina bifida
AI ApproachIndividual and ensemble model (Random forest, CNN from tracing and imaging, respectively) 
Data Source(s)Single institutional series (306 VUDS from 256 patients)
Model InputClinical: Age, Pressure at 25, 50, 75% EBC; presence of VUR, leak, bladder shape, detrusor sphincter dyssynergia, post-void residual, %EBC achieved

Urodynamics: Tracings at 25, 50, 75% EBC; detrusor pressures

VUDS: Fluoroscopic images
Model OutcomeMild vs. moderate vs. severe dysfunction
Model MetricsEnsemble model, accuracy of 75%

No/mild: AUC of 0.75-0.85; Moderate dysfunction: AUC of 0.64-0.75;
Severe dysfunction: AUC of 0.82-0.89
Model UsabilityNA

AI = Artificial intelligence; LUTD = Lower urinary tract dysfunction, CNN = Convolutional neural network, VUDS = Video urodynamics

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