Renal scarring in lower urinary tract dysfunction, Misc.

Article DOIhttps://doi.org/10.28982/josam.691768
ObjectiveTo predict renal scarring in children with LUTD
AI Approach7 models were tested: ANN and XGB were superior
Data Source(s)Single institutional series (75 patients)
Model InputClinical Features (episodes of symptomatic UTI, presence of VUR, bladder trabeculation, bladder wall thickness, catherization), VUDS Features (post-void residual volume, bladder volume, wall thickness, compliance, detrusor hyperactivity, reduced bladder capacity, detrusor leak point pressure, DMSA Features (differential function of less than 40%, presence of renal scarring and/or atrophy)
Model OutcomePresence of renal scarring
Model MetricsSMOTE data: AUROC 0.90 and 0.88 for ANN and XGB
sensitivity 88% and 82% for ANN and XGB;
specificty 94% and 93% for ANN and XGB.
Model UsabilityNA
AI = Artificial intelligence; LUTD = Lower urinary tract dysfunction, ANN = Artificial neural network, XGB = Gradient boosting

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